منابع مشابه
Metagenomics for mining new genetic resources of microbial communities.
Recent progress has revealed that the capture of genetic resources of complex microbial communities in metagenome libraries allows the discovery of a richness of new enzymatic diversity that had not previously been imagined. Activity-based screening of such libraries has demonstrated that this new diversity is not simply variations on known sequence themes, but rather the existence of entirely ...
متن کاملMetagenomics and Microbial Communities
Metagenomics is the genomic analysis of microbial communities. This new science provides access to organisms that are recalcitrant to culturing, as are the vastmajority of microorganismsonEarth.Metagenomics therebyoffers a first peek at thewide varietyof life that has never been studied, thus providing new insight into the structure and function of ecosystems as diverse as the oceans and the hu...
متن کاملComparative metagenomics of microbial communities.
The species complexity of microbial communities and challenges in culturing representative isolates make it difficult to obtain assembled genomes. Here we characterize and compare the metabolic capabilities of terrestrial and marine microbial communities using largely unassembled sequence data obtained by shotgun sequencing DNA isolated from the various environments. Quantitative gene content a...
متن کاملMetagenomics: genomic analysis of microbial communities.
Uncultured microorganisms comprise the majority of the planet's biological diversity. Microorganisms represent two of the three domains of life and contain vast diversity that is the product of an estimated 3.8 billion years of evolution. In many environments, as many as 99% of the microorganisms cannot be cultured by standard techniques, and the uncultured fraction includes diverse organisms t...
متن کاملIs metagenomics resolving identification of functions in microbial communities?
We are coming up on the tenth anniversary of the broad use of the method involving whole metagenome shotgun sequencing, referred to as metagenomics. The application of this approach has definitely revolutionized microbiology and the related fields, including the realization of the importance of the human microbiome. As such, metagenomics has already provided a novel outlook on the complexity an...
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ژورنال
عنوان ژورنال: Journal of Molecular Microbiology and Biotechnology
سال: 2009
ISSN: 1660-2412,1464-1801
DOI: 10.1159/000142898